ARTICLE –
abstractLifestyle
intervention improve clinical features and metabolic profiles in
patients with metabolic syndrome Suzana Dănoiu1, Anca
Rizea1, Mircea Danoiu2,
Rucsandra Dănciulescu Miulescu3, Cătălina Poiană3,
Denisa Margină3 1UMF
Craiova,Romania 2University of Craiova,
Romania 3UMF Carol Davila Bucharest,
Romania
Abstract
Background
and Aims. The term “Metabolic Syndrome”
is a clinical entity of substantial heterogeneity, represented by the
co-occurrence of multiple metabolic and vascular disorders than are
risk factors for type 2 diabetes mellitus and atherosclerotic
cardiovascular diseases Exercise has long been recognized as an
important factor in the treatment of metabolic syndrome. We
investigated the effects of exercise and calorie restriction in
patients with metabolic syndrome who participated in a observational,
24-week study. Materials and Methods: 36
patients with metabolic syndrome (female 22 and male 14) were recruited
for this study. The subjects were between 42 and 64 years.
Anthropometric and biochemical parameters were assessed.
Blood pressure was recorded. The metabolic syndrome was defined
according the International Diabetes Federation. The recommendations to
all patients were to improve lifestyle by reducing caloric intake and
increase of exercise. As a general direction a diet with 500 kcal/day
less than the previous one was recommended. Patients heave exercised
regularly: walking or running for 30 min 2-4 times a week. Results.
This study showed that exercise and diet was efficacious in improving
waist circumference (96.25 ± 7.34 cm vs. 96.25 ±
7.34 cm, p < 0.05) systolic blood pressure (142.26 ±
10.12 mmHg vs. 134.44 ± 9.72 mmHg, p < 0.05), serum
trigycerides (188.55 ± 33.12 mg/dl vs. 142.16 ±
24.32 mg/dl, p < 0.05), fasting glucose (102.40 ±
12.02 mg/dl vs. 89.20 ± 11.10 mg/dl, p < 0.05). There
was essentially no change in the mean diastolic blood pressure and
serum HDL cholesterol of the patients throughout the study. Conclusion.
This study showed that exercise and diet was efficacious in improving
waist circumference, systolic blood pressure, serum trigycerides,
fasting glucose.
Key
words:metabolic
syndrome, exercise, diet.
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