Study of the effect induced by physical effort on urinary malonyldialdehyde level on the unschooled young male (smoker and non-smoker)

Radu MD 1,2 , Chirică R 3 , Șapte Elena 4
1 Faculty of Natural and Agricultural Sciences, Ovidius University of Constanta,
2 Faculty of Pharmacy, Ovidius University of Constanta,
3 Faculty of Medicine, Ovidius University of Constanta,
4 Faculty of Dental Medicine, Ovidius University of Constanta, Romania


The beneficial effects of physical effort are known and demonstrated largely on both clinical and non-clinical experimental models. Currently, clinicians recommends physical effort to patients with acute or chronic pathologies and also those under medication. During physical effort, reactive chemical species of oxygen (oxygen free radicals) are generated, and that induce irreversible damage to cells. The oxidative stress generated by the increase in free oxygen concentration and inflammation induced by physical effort is not only about anatomical structures directly involved in supporting physical effort, but also about other organs involved in post-exercise metabolic recovery, or in the elimination of metabolic products , as is these case, the excretory system. The mechanism by which physical effort induces the appearance of transient renal pathologies has as starting point, the free radicals of oxygen and the cascade of reactions that are induces. Malondialdehyde is an indicator of the degree of peroxidation of lipids in the cell membrane structure. The level of malondialdehyde increases only when major destruction of biological membranes occurs. Urinary malondialdehyde gives us information about both, the renal functional status and the general physiological status of the body, undergoing repetitive exercise. The experimental data obtained revealed that in our experimental model the physical effort does not induce the statistically significant increase of the level of urinary malonyldialdehyde in the two experimental groups that was studied. This information indicates that from the metabolic point of view the smoker or non-smoker body can adapt and respond specifically to the new physiological requirements imposed by the medium intensity repetitive effort.

Key words:

exercise, oxidative stress, urinary malonyldialdehyde

Full article:

Study of the effect induced by physical effort on urinary malonyldialdehyde level on the unschooled young male (smoker and non-smoker)


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