antioxidant enzymes in young exercised women
Erfani Karimzadeh Toosi A1, Rezaei A2, Sariri Kh R3
1 Gastrointestinal and Liver Disease Research Center, Guilan University of Medical Sciences, Rasht, Iran
2Department of Periodontology, Faculty of Dentistry, Tehran University of Medical Sciences, Tehran, Iran
3 Department of Microbiology, Lahijen Branch, Islamic Azad University, Lahijan, Iran
Saliva is the first body fluid to encounter different solids, fluids
and gases entering the gastrointestinal tract. Human saliva is composed
of various natural antioxidants including enzymatic and non-enzymatic
systems. Free radicals are naturally produced species with an unpaired
electron, i.e. reactive towards biological molecules. Production of
these reactive species is affected by different factors including
metabolic and various external events. An important consequence of
aerobic exercise is related to increased antioxidant capacity of human
body. In the present research, antioxidant enzymes in salivary fluid of
young girls were investigated after aerobic exercise.
Material and Method.
A volunteer group of 35 healthy female university students (mean age
25.1▒1.5 years) entered the study. They were told to attend a one month
course of aerobic training. Three samples of their saliva were obtained
at the beginning of research, after two weeks and at the end of
exercise period. The activity of three antioxidant enzymes, catalase,
superoxide dismutase and peroxidase were assayed in supernatant of
their centrifuged saliva samples.
Results. A significant increase in the activity of three antioxidant enzymes was observed.
The increase in oxidative free radicals induced by exercise is
compensated by higher activity of antioxidant enzymes of saliva.
Therefore, enzymatic activity is salivary fluid could be a marker of
oxidative status of saliva due to production of free radicals. Aerobic
exercise for a month stimulates the activity of antioxidant enzymes in
favor of radical scavenging ability.
saliva, aerobic exercise, catalase, peroxidase, superoxide dismutase