GUIDE
ARTICLES – abstract Mechanisms
of localizated muscle fatigue during maximal isometric contraction Vasilescu
Maria Mirela, Rusu Ligia, Rinderu Taina University
of Craiova, Kinetotherapy Abstract In
contrast to fatigue involving
the whole body, the phenomenon
of localized muscle
fatigue is most commonly described as occurring when the muscle
can no longer maintain the required force level due to exercise. The
physiological causes of fatigue have been classified as
either ,,peripheral” or ,,central”. The peripheral
skeletal
muscle fatigue is defined as a decrease in the capacity of
the skeletal muscle to generate force because of action
potential failure, excitation - contraction coupling
failure, or impairment of cross bridge cycling, in the
presence of unchanged or increasing neural drive. In contrast,
central fatigue has been defined as a reduction in neural
drive to the muscle resulting in a decline in force production
or tension development that is independent of changes in
skeletal muscle contractility. This article briefly
explains the mechanism of peripheral skeletal muscle fatigue based on
scientific literature dates.
Key
words: muscle fatigue, ATP, Ca2+,
pH, inorganic
phosphate, lactic acid.
|